f POP: footprinting functional pockets of proteins by comparative spatial patterns
نویسندگان
چکیده
منابع مشابه
fPOP: footprinting functional pockets of proteins by comparative spatial patterns
fPOP (footprinting Pockets Of Proteins, http://pocket.uchicago.edu/fpop/) is a relational database of the protein functional surfaces identified by analyzing the shapes of binding sites in approximately 42,700 structures, including both holo and apo forms. We previously used a purely geometric method to extract the spatial patterns of functional surfaces (split pockets) in approximately 19,000 ...
متن کاملComparative footprinting of DNA-binding proteins
MOTIVATION Comparative modelling is a computational method used to tackle a variety of problems in molecular biology and biotechnology. Traditionally it has been applied to model the structure of proteins on their own or bound to small ligands, although more recently it has also been used to model protein-protein interfaces. This work is the first to systematically analyze whether comparative m...
متن کاملFormal-comparative analysis of the spatial organization of student residence halls based on their spatial threshold patterns
Functional quality of the student residence halls has a great deal of importance due to their collective nature and the fact that they are considered as housing units, identifying and defining the role of intermediary spaces on the spatial organization and and spatial consociation of student residence halls which is a compound system of masses and spatial borderlines can bring order to its syst...
متن کاملFinding functional features in Saccharomyces genomes by phylogenetic footprinting.
The sifting and winnowing of DNA sequence that occur during evolution cause nonfunctional sequences to diverge, leaving phylogenetic footprints of functional sequence elements in comparisons of genome sequences. We searched for such footprints among the genome sequences of six Saccharomyces species and identified potentially functional sequences. Comparison of these sequences allowed us to revi...
متن کاملa comparative move analysis of the introduction sections of ma theses by iranian and native post-graduate students
since esp received universal attention to smooth the path for academic studies and productions, a great deal of research and studies have been directed towards this area. swales’ (1990) model of ra introduction move analysis has served a pioneering role of guiding many relevant studies and has proven to be productive in terms of helpful guidelines that are the outcome of voluminous productions ...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2009
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkp900